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List of games that support Crossfire

From PCGamingWiki, the wiki about fixing PC games

Project aim

Name Notes
Age of Conan
Age of Empires Online
Age of Wonders 2
Age of Wonders: Shadow Magic
Air Missions: HIND use "optimize 1X1" CROSSFIREX option, never use VSync in game options, maybe not use anti aliasing in game.
Alan Wake Excellent scaling, minimal microstutter
Alan Wake's American Nightmare
Alice: Madness Returns
Alien Breed: Impact
Alien: Isolation Engine suffers from heavy aliasing, saw-toothing and shimmering issues. Use VSR
Aliens: Colonial Marines
Aliens vs. Predator (2010)
All Points Bulletin
American Truck Simulator Tested with two RX 480 at 1440p. Create a profile and select AFR friendly mode, also activate V-SYNC, it gets rid of some flickering. If some still exists, try lowering reflection detail.
Apex Legends Tested with two RX470 at 1920*1080.Create a profile and select 1X1 Optimized mode, I get average 144 FPS With all settings at low or off, except for the view distance at max.
America's Army 3
Anno 2070 CPU bound game
Arcania: Fall of Setarrif
Arcania: Gothic 4
Arma 2: Operation Arrowhead
Arma 3 Game stayed CPU bound regardless of settings, performance improvement was minor.
Armored Warfare
Ashes of the Singularity Rather noticeable graphical bugs and glitches present on DX12 mode, not exclusive to multi GPU
Assassin's Creed Unstable use of 6990m CF (30 fps in towns on ultra settings)
Assassin's Creed II
Assassin's Creed IV: Black Flag Poor use of 6990m CF (erratic use, from 50% to 100% - 20 fps in towns on ultra settings) - the 2nd card was barely used until overclocked with AMD Overdrive
Assassin's Creed: Brotherhood
Assassin's Creed: Revelations
Assassin's Creed Rogue
Assassin's Creed: Unity Game is very CPU intensive, Low render distance caused by the engine, fixed in Win 10
Assassin's Creed Odyssey
Assetto Corsa
Batman: Arkham Origins Tested with RX480's, able to achieve over 100 FPS @ 2160p in some parts. Using AFR mode for Crossfire and capping framerate to monitor's refresh rate can smooth out performance.
Battlefield 1 TAA +post processing above medium cause crossfire issues. Use FXAA or no AA.

Note: this game is very heavily CPU-dependent by means of IPC and multi-core performance.

Battlefield 3
Battlefield 4 The game may crash frequently when using Mantle and Crossfire at the same time, no issues using DirectX renderer
Battlefield V
Battlefield: Bad Company 2
Battlefield Hardline
BattleForge Fan continuation is called Skylords Reborn
Ba San Guo
BioShock 2
BioShock Infinite
Black Mesa
Blacklight: Retribution
Blade & Soul
Borderlands 2
Borderlands 3
Burnout Paradise Remastered
Call of Duty: Advanced Warfare
Call of Duty: Black Ops
Call of Duty: Black Ops II
Call of Duty: Black Ops III
Call of Duty: Ghosts
Call of Juarez
Call of Juarez: Bound in Blood
Call of Juarez: Gunslinger Improved scaling, occasional minor microstutter (1080p)
Car Mechanic Simulator 2015 Default mode" set in crossfire mode in game profile
Cars 2
Champions of Regnum
Cities: Skylines
Company of Heroes
Counter-Strike: Global Offensive
Crash Bandicoot N. Sane Trilogy Just set everything as you wish and in exclusive fullscreen mode, then for testing I suggest removing the 60 FPS cap as explained in the PC GAMING WIKI. (double performance with 2 R9 290 at 4K, no AA).
The Crew
Crysis 2
Crysis 3 Great for benchmarking graphics cards
Dark Souls
Dark Souls II: Scholar of the First Sin Works well if you want to play in resolutions above 1080p.
Dark Souls 3
Darksiders II
Darksiders III
The Darkness II Not really performance-intensive. Use GeDoSaTo to get maximum image quality by downsampling (set forceAlwaysDownsamplingRes to true though!)
Dark Void
Dead Rising
Dead Rising 2
Dead Rising 3 Requires forcing TESV CF profile. Game does not officially support multi-GPU.
Depth Hunter
Deus Ex: Human Revolution The Missing Link and the Director's Cut versions have no native profile - Force 'regular' DXHR profile (DX3_win32_final.exe)
Deus Ex: Mankind Divided
Dexter: The Game
Devil May Cry 4
DmC: Devil May Cry
Devil May Cry 5
Diablo III
Disciples II: Dark Prophecy
Dishonored 2
DiRT 2
DiRT 3
DiRT Rally Default profile works great
DiRT Showdown
The Division TAA Off, Flickers removed, Noticeable Framerate difference, +~ 20 FPS Average 2xR9furyx
Doom (2016)
Doom 3
Dota 2 120 fps cap
Dragon Age II
Dragon Age: Inquisition
Dragon's Dogma: Dark Arisen No profile, default crossfire mode yields better performance than AFR / 1x1.
Dragon Quest XI Use Obduction Profile
Drakensang: The Dark Eye
Duke Nukem Forever
Dungeons & Dragons: Daggerdale
Dungeon Siege III
Dva Mira II
Dying Light Flickering is experienced on screen effects, disabling Nvidia's depth of field might solve this issue.
The Elder Scrolls Online Force Optimize 1x1, play in DX11 mode (DX9 exclusive FS is bugged)

Towns and PvP are heavily reliant on single core CPU perf (but x64 and DX12 patch planned)

Elite: Dangerous Tested with r7 260X crossfire
Enemy Territory: Quake Wars
Entropia Universe
Euro Truck Simulator 2 Tested with two RX 480 at 1440p. Create a profile and select AFR friendly mode, also activate V-SYNC, it gets rid of some flickering. If some still exists, try lowering reflection detail.
Everybody's Gone to the Rapture
F1 2010
F1 2011
F1 2012
F1 2013
F1 2014
F1 2015
F1 2016 Use SMAA instead of TAA otherwise you'll get horrible crossfire scaling.
Fable 3
Fallout 4 Force Optimize 1x1, Set AA to TXAA. CPU bound scenes lose FPS, most areas gain FPS, but suffers from increase stutter.
Fallout New Vegas Limited to 86fps, game physics tied to the framerate.
Far Cry 2
Far Cry 3 CPU bound game
Far Cry 4 Tested with RX480's with resolution up to 2160p.
Far Cry Primal
Far Cry 5
F.E.A.R. 3
FlatOut: Ultimate Carnage
Final Fantasy XII: The Zodiac Age
For Honor
Forza Motorsport 6: Apex
Forza Horizon 3
Free Falcon 6
Front Mission Evolved
Garshasp: The Monster Slayer
Gas Guzzlers Extreme
Gears of War
Gears of War: Ultimate Edition
Gears of War 4 Enable CFX on global settings,unlock FPS and enable fps counter in game options, after benchmark return to MSI aft. to see second GPU was used, works well with Eyefinity too
Global Agenda
Global Ops: Commando Libya
Gothic 3
Grand Theft Auto 5 crashes may be experienced when Alt+Tab -ing from fullscreen
GRID Autosport
Grotesque Tactics: Evil Heroes
Guild Wars 2
Hard Reset
Homefront: The Revolution Forcing any CF mode & using CryEngine 3&4 profile games don't work. SLI only title.
Insane 2
James Bond 007: Blood Stone
James Cameron's Avatar: The Game
Just Cause 2
Just Cause 3
Kane & Lynch 2: Dog Days
Killer Instinct
Killing Floor 2
Kingdoms of Amalur: Reckoning
Kritika Onlnie
L.A. Noire
Left 4 Dead 2
Legends of Aethereus
Lego Harry Potter: Years 1-4
Lego Harry Potter: Years 5-7
Lego Pirates of the Caribbean: The Video Game
Lichdom: Battlemage Don't change the image quality after load a save, this will give you a poor performance until you restart the game. Recommended to use the crossfire profile.
Lord of the Rings Online
Lords of the Fallen
Lost Planet
Lost Planet: Extreme Condition Colonies Edition
Lost Planet 2
Lost Planet 3 You can use any mode, also Lost Planet 2 official profile
Mad Max AFR friendly mode yields better performance than Default & Optimize 1x1. Flickering in map view only.
Mafia II
Mass Effect 2 AFR Friendly
Mass Effect 3
Mass Effect: Andromeda Multi GPU can be enabled from command line using "-RenderDevice.AmdCrossfireEnable 1"
Max Payne 3
MechWarrior Online
Medal of Honor (2010)
Medal of Honor: Warfighter
Medieval II: Total War
Medieval II: Total War: Kingdoms
Metal Gear Solid V: Ground Zeroes
Metal Gear Solid V: The Phantom Pain capped at 60fps, removing the cap causes variable mouse speeds making the game unplayable Effects quality at Very High may cause large framerate drops
Metro 2033
Metro 2033 Redux Excellent scaling, minimal microstutter
Metro: Last Light
Microsoft Flight
Microsoft Flight Simulator X
Middle-earth: Shadow of Mordor
Minecraft AFR Friendly Mode
Mirror's Edge Capped at 60, can be removed with an ini tweak.
Mirror's Edge Catalyst
Monster Hunter World Default Mode: Single GPU

AFR Friendly: Positive 80% scaling but with flickering & artifacts. Optimized: Negative 36% AFR Compatible: Negative 40%

Mount & Blade
Mount & Blade: Warband
Mount & Blade: With Fire & Sword
Murdered: Soul Suspect
Natural Selection 2
NBA 2K11
NBA 2K12
Need for Speed Payback
Need for Speed (2016)
Need for Speed: Hot Pursuit
Need for Speed: Most Wanted Capped at 60, good FPS increase, max settings except supersampling 2X(tested with 2xR9 290, 2 screens, 3840x1080)default profile cannot even launch the game, create a new game profile manually pointing to NFS13.exe, then set manually to use Need for Speed the Run profile.
Need for Speed: The Run
Nexuiz (2012)
Nier: Automata Create a profile in Radeon Settings and use CFX profile of Final Fantasy XII The Zodiac Age. Works well with EyeFinity too. Warmly suggested the use of FAR (mod) (set to high or medium illumination in FAR for more performance).
Oil Rush
Overwatch Double framerate with default profile (Tested with 2x RX480 at 1080p. You need to turn on afr friendly mode in the crimson setting and if it keeps flickering exit the game and go back it and it should be fine but keep in mind the characters hair might have minor glitches.
PlanetSide 2
Plants vs. Zombies: Garden Warfare
Plants vs. Zombies: Garden Warfare 2 Good scaling, Average microstutter
Portal 2
Prey (2017)
Project CARS The game actually performs really well, also allows you to change flip queue size between 1 to 4. Default "2" works really well.
Project CARS 2 Excellent scaling, no noticeable microstutter
Pro Cycling Manager 2015
Quantum Break
Quake IV
Rainbow Six Siege Negative scaling, Heavy microstutter
Red Dead Redemption 2
Red Faction: Armageddon
Red Orchestra 2: Heroes of Stalingrad
Reign of Thunder
Resident Evil Use ESC key to skip opening cutscenes or the main menu will glitch.
Resident Evil 5
Resident Evil 6
Resident Evil 7
Rise of Flight: The First Great Air War
Rise of the Tomb Raider Excellent scaling, minimal microstutter.
Rise of the Triad
Risen 2: Dark Waters
Rocket League
Rome: Total War
Rugby World Cup 2015
Ryse: Son of Rome Some shiny surfaces have a slight flicker. Game has odd Vsync issues
Saints Row IV No scaling at 1080p
Saints Row: The Third
Scum Tested with the lowest possible settings on an R9 295x2 with optimize 1x1. Game does have some visual glitches for a couple of minutes, though they will disappear after some time.
Serious Sam HD: The First Encounter
Serious Sam HD: The Second Encounter
Serious Sam 3
Shadow of Mordor
Shadow of the Tomb Raider default dx12afr,disable vsync,the shadow turn to low or disable.
Shadow Warrior (2013)
Shaun White Skateboarding
Shift 2 Unleashed
Sid Meier's Civilization V Good scaling at 1440p with 8x MSAA, not recommended for lower resolutions.
Sid Meier's Civilization VI
Sid Meier's Civilization: Beyond Earth
Silent Hunter 5: Battle of the Atlantic
SiN Episodes: Emergence
Sniper Elite V2
Sniper Elite 3
Sniper Elite 4
Spec Ops: The Line
Sleeping Dogs
S.T.A.L.K.E.R.: Call of Pripyat Frequent stutters due to poor multi threading
S.T.A.L.K.E.R.: Clear Sky Frequent stutters due to poor multi threading
Starcraft 2 Game heavily reliant on single core CPU performance
Star Citizen
Star Wars Battlefront In driver 17.6.2]Excellent scaling, major flickering in post-match screen; texture corruption if Afterburner/Rivatuner OSD is active (disable it in RTSS); noticeable flickering in the tunnels of Hoth map; less-than-expected performance only into the Death Star map.
Star Wars: The Old Republic
Supreme Commander: Forged Alliance
Syndicate (2012)
Tekken 7 Force official "Dreadnought" profile on Tekken 7.exe and TekkenGame-Win64-Shipping.exe both
Test Drive: Ferrari Racing Legends
Test Drive Unlimited 2
The Crew
The Elder Scrolls V: Skyrim Game engine is CPU limited
The First Templar
The Forest Only works with AFR friendly mode and V-Sync. Some flickering in inventory.
The Next Big Thing
The Outer Worlds
The Park
The Secret World
The Sims Medieval
The Talos Principle DX9 API has considerably worse performance than DX11, and is not recommended.
Titanfall 2 Good scaling. Terrible stutter (occasional)
Tomb Raider
Tomb Raider (2013)
Tom Clancy's Ghost Recon: Future Soldier
Tom Clancy's Ghost Recon Wildlands
Tom Clancy's H.A.W.X
Tom Clancy's H.A.W.X 2
Tom Clancy's Splinter Cell: Blacklist
Tom Clancy's Splinter Cell: Conviction
Torchlight 2
Total War: Attila
Total War: Rome II
Total War: Shogun 2 *Scales well as long as GPU bound, MSAA recommended
Total War: Warhammer
The Witcher 2: Assassins of Kings Ubersampling stays extremely performance intensive even on Crossfire. Towns are CPU bound. Poor use of 6990m CF (50 % use - 15 fps max).
The Witcher 3: Wild Hunt Extreme flickering on textures 50/50 of the time when loading save. Pre-rendered cut-scenes have awful microsutter
theHunter: Call of the Wild Set shadows to High to remove shadow flickering
TrackMania 2: Valley
Tribes: Ascend
Tron: Evolution
Two Worlds 2
XCOM: Enemy Unknown Negative scaling at 1080p, try higher resolutions
XCOM 2 Performance problems related to the game itself.
War Inc. Battlezone
War of the Roses
Wargame: European Escalation
Wargame: Airland Battle Use wargame.exe Profile
Wargame: Red Dragon Use wargame.exe Profile
Warhammer: Vermintide 2
Warhammer 40,000: Space Marine
Watch_Dogs 2
Wolfenstein: The New Order
World in Conflict
World of Tanks Disable any FXAA or TSSAA (both cause negative scaling).
World of Warcraft
Wolfenstein: Youngblood