Grand Theft Auto: San Andreas
Issues and Fixes
Game Crashes when Cars Explode
This problem usually occurs on Windows Vista and Windows 7 when running the game with x32 graphics. The simplest solution is to run it in x16 graphics however the game will look much worse. To properly fix it, run the game in an older compatibility mode. To do this, right-click the .exe, open Properties and set the game to run in Windows 2000 compatiblity mode from the Compatibility tab. If running the steam version you will need to set the compatibility mode to Windows 2000 or Steam will not launch the game properly. You will likely find the .exe in:
C:\Program Files (x86)\Steam\steamapps\common\grand theft auto San Andreas