Topic on Talk:Red Dead Redemption 2
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Just gave it a try and seems not :( Switched to Online on the menu and tried loading in, load screen showed up for a few seconds but then gave the same error.
(strange that my bugged SP save would effect the online part, maybe because I haven't set up my online chara yet or something...)
Removed the cache files & tried again, and it loaded in fine.
Too bad, that would have been a better fix. Sounds like it can help for some people though, could still be worth mentioning it I guess.