I also tried it on my older Windows 10 PC with dedicated graphics (GTX 1070) and it works but the FMVs flicker on the first time I started it up, after starting it up multiple times after messing with the compatibility properties and then disabling all the compatibility options, the FMVs no longer flicker but the screen is really small and windowboxed (on my 1080p monitor). No wonder why it won't run on Windows 11 though while it can on 10? Does it need graphics by Nvidia or AMD (since Intel graphics are new)? Or is it due to the fact that Windows 11 officially requires aspect ratios wider than 4:3? I thought Win 11 would have similar functions to 10?
I wish this game gets another remaster (like what Nightdive did to Shadow Man 8 years after releasing the original version in 2013) which should get even further upscaled cutscenes and officially support multiple resolutions higher than 640x480 (though it should stay pillarboxed on wider ratio resolutions (like 1920x1080) as it's a pre-rendered game with sprites and fixed non-moving camera positions). Also, I think it should stop using QuickTime and use a more common third-party video engine that isn't by Microsoft or Apple, so it could support multiple OSs without trouble. Like most other modern games and remasters nowadays, this game should support 64-bit and drop 32-bit, especially on modern Mac OSs which doesn't support 32-bit apps anymore.